Deglin JH, Vallerand AH.
Davis's Drug Guide for Nurse
s. 12th ed. FA Davis
Company: Philadelphia, PA; 2010.
Wei ZH, Wang H, Chen XY, et al. Time- and dose-dependent
effect of psyllium on serum lipids in mild-to-moderate hypercholesterolemia: a
meta-analysis of controlled clinical trials.
Eur J Clin Nutr. 2009 Jul;63(7):821-827.
Ganji V, Kuo J. Serum lipid responses to psyllium fiber: differences between pre- and post-menopausal,
Nutr J. 2008;7:22.
Cicero AF, Derosa G, Manca M, Bove M, Borghi C, Gaddi AV. Different effect of psyllium and guar dietary supplementation on blood pressure control
in hypertensive overweight patients: a six-month, randomized clinical trial.
Clin Exp Hypertens. 2007 Aug;29(6):383-394.
Sierra M, García JJ, Fernández N, Diez MJ, Calle AP. Therapeutic effects
of psyllium in type 2 diabetic patients.
Eur J Clin Nutr. 2002 Sep;56(9):830-842.
Shaffer EA, Edwards AL, Brant R, Van Rosendaal GM. Effect of time of administration on cholesterol-lowering by psyllium: a randomized
cross-over study in normocholesterolemic or slightly hypercholesterolemic
Nutr J. 2004 Sep 28;3:17.
Sprecher DL, Harris BV, Goldberg AC, et al. Efficacy of
psyllium in reducing serum cholesterol levels in hypercholesterolemic patients on high- or
Ann Intern Med. 1993 Oct 1;119:545-554.
Ramkumar D, Rao SS. Efficacy and safety of traditional
medical therapies for chronic constipation: systematic review.
Am J Gastroenterol. 2005 Apr;100(4):936-971.
Bijkerk CJ, Muris JW, Knottnerus JA, Hoes AW, de Wit NJ. Systematic review: the role of different types of fibre in the treatment of irritable
Aliment Pharmacol Ther. 2004 Feb 1;19(3):245-251.
Marlett JA, Li BU,
Patrow CJ, Bass P.
Comparative laxation of psyllium with and without senna in an ambulatory constipated
Am J Gastroenterol. 1987 Apr;82(4):333-337.
Cheskin LJ, Kamal N,
Crowell MD, Schuster
MM, Whitehead WE. Mechanisms of
constipation in older persons and effects of fiber compared with placebo.
J Am Geriatr Soc. 1995 Jun;43(6):666-669.
Ashraf W, Park F, Lof J, Quigley EM. Effects of
psyllium therapy on stool characteristics, colon transit and anorectal function in chronic
Ther. 1995 Dec;9(6):639-647.
Odes HS, Madar Z. A
double-blind trial of a celandin, aloe vera, and psyllium laxative preparation in adult
patients with constipation.
McRorie JW, Daggy BP,
Morel JG, et al. Psyllium is superior to docusate
sodium for treatment of chronic constipation.
Aliment Pharmacol Ther. 1998 May;12(5):491-497.
University of Maryland Medical Center. Psyllium. University of Maryland
Medical Center website. Available at:
http://www.umm.edu/altmed/articles/psyllium-000321.htm. Updated May 6, 2009. Accessed September 22, 2010.
Uehleke B, Ortiz M,
Stange R. Cholesterol reduction using psyllium husks—do
gastrointestinal adverse effects limit compliance? Results of a specific observational
Phytomedicine. 2008 Mar;15(3):153-9.
Petchetti L, Frishman WH, Petrillo R, Raju K. Nutriceuticals in
cardiovascular disease: psyllium.
Cardiol Rev. 2007 May-Jun;15(3):116-22.
Shrestha S, Freake
HC, McGrane MM, Volek
JS, Fernandez ML. A combination of
psyllium and plant sterols alters lipoprotein metabolism in hypercholesterolemic subjects
by modifying the intravascular processing of lipoproteins and increasing LDL uptake.
J Nutr. 2007 May;137(5):1165-70.
Ziai SA, Larijani B, Akhoondzadeh S, et al. Psyllium decreased serum glucose and
glycosylated hemoglobin significantly in diabetic outpatients.
Ethnopharmacol. 2005 Nov 14;102(2):202-7.
Moreno LA, Tresaco B,
Bueno G, et al. Psyllium fibre and the metabolic control
of obese children and adolescents. J
Biochem. 2003 Sep;59(3):235-42.
Bulk-forming laxatives. DynaMed website. Available at:
http://www.ebscohost.com/dynamed/what.php. Updated June 26, 2010. Accessed September 27, 2010.
Bijkerk CJ, de Wit
NJ, Muris JW, et al. Soluble or insoluble fibre
in irritable bowel syndrome in primary care? Randomised placebo controlled trial.
BMJ. 2009 Aug 27;339.
Bliss DZ, Jung HJ,
Savik K, et al. Supplementation with dietary fiber
improves fecal incontinence.
Nurs Res. 2001 Jul-Aug;50(4):203-13.
Anderson JW, Allgood
LD, Lawrence A, et al. Cholesterol-lowering
effects of psyllium intake adjunctive to diet therapy in men and women with
hypercholesterolemia: meta-analysis of 8 controlled trials.
Am J Clin Nutr. 2000 Feb;71(2):472-9.
Burke V, Hodgson JM,
Beilin LJ, et al. Dietary protein and soluble fiber
reduce ambulatory blood pressure in treated hypertensives.
Hypertension. 2001 Oct;38(4):821-6.
Psyllium. National Center for Biotechnology
States National Library of Medicine website. Available at:
http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000092. Updated February 1, 2009. Accessed September 28, 2010.
Suares NC, Ford AC.
Systematic review: the effects of fibre in the management of chronic idiopathic constipation.
Aliment Pharmacol Ther.
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