In its early phases, chronic kidney disease usually doesn’t cause symptoms. However, as the condition progresses to the end-stage renal disease stage, it can cause a number of symptoms, including:
- Feeling weak or tired
- Trouble sleeping
- Swelling of feet and ankles
- Poor appetite
- Needing to urinate more often, especially at night
- Muscle cramping at night
- Shortness of breath
- Metallic taste in mouth
- Chest pain
- Difficulty concentrating
- Reduced interest in sex
- Menstrual irregularities
- Numbness and tingling in hands and feet
Are you at increased risk for chronic kidney disease? National Kidney Foundation website. Available at:
http://www.kidney.org/atoz/pdf/11-10-1814.pdf. Published 2010. Accessed July 2, 2013.
Chronic kidney disease. EBSCO DynaMed website. Available at:
https://dynamed.ebscohost.com/about/about-us. Updated April 22, 2013. Accessed July 2, 2013.
Chronic kidney disease: patient information handout. American Academy of Family Physicians website. Available at:
http://familydoctor.org/online/famdocen/home/common/kidney/832.html. Updated November 2010. Accessed July 2, 2013.
National Kidney Foundation. Kidney Disease Outcomes Quality Initiative (K/DOQI) clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification.
Am J Kidney Dis.
Snyder S, Pendergraph B. Detection and evaluation of chronic kidney disease.
Am Fam Physicians.
Last reviewed July 2013 by Adrienne Carmack, MD; Michael Woods, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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