Hartford Hospital

Conditions In Depth

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In its early phases, chronic kidney disease usually doesn’t cause symptoms. However, as the condition progresses to the end-stage renal disease stage, it can cause a number of symptoms, including:

  • Feeling weak or tired
  • Trouble sleeping
  • Swelling of feet and ankles
  • Poor appetite
  • Needing to urinate more often, especially at night
  • Muscle cramping at night
  • Nausea
  • Itching
  • Shortness of breath
  • Metallic taste in mouth
  • Chest pain
  • Altered mental state
  • Hiccups
  • Irritability
  • Problem with concentration
  • Reduced libido
  • Menstrual irregularities
  • Numbness and tingling in hands and feet

References:

Are you at increased risk for chronic kidney disease? National Kidney Foundation website. Available at: http://www.kidney.org/atoz/pdf/11-10-1814.pdf. Accessed September 10, 2011.

Chronic kidney disease: patient information handout. American Academy of Family Physicians website. Available at: http://familydoctor.org/online/famdocen/home/common/kidney/832.html. Accessed September 10, 2011.

National Kidney Foundation. Kidney Disease Outcomes Quality Initiative (K/DOQI) clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Am J Kidney Dis. 2002;39:S1-266.

Snyder S, Pendergraph B. Detection and evaluation of chronic kidney disease. Am Fam Physicians. 2005;72:723-732.

Last reviewed September 2012 by Adrienne Carmack, MD

Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.